Friday's leading pre-market gainers and losers

Here are the biggest percentage gainers and losers in Friday’s pre-market trading among companies with a market cap between $50 million and $750 million:

Biggest percentage gainers:

• Progenics Pharmaceuticals, Inc. (Nasdaq:PGNX), up 23.7% after the Tarrytown, N.Y.-based company’s constipation drug won FDA approval.

• Pure Bioscience (Nasdaq:PURE), up 18.6% on no significant news from the El Cajun, Calif.-based bio-science firm.

• YRC Worldwide Inc. (Nasdaq:YRCW), up 12.7% after the transportation services company said early Friday that it expects second-quarter profit in-line with Wall Street expectations.

Biggest percentage losers:

• SiRF Technology Holdings Inc. (Nasdaq:SIRF), down 14.1% after posting a wider-than-expected first-quarter loss.

• ScanSource, Inc. (Nasdaq:SCSC), down 12.5% after reporting that it expects fourth-quarter revenue in the range of $540 million to $560 million. Wall Street anticipates $562.7 million.

• UCBH Holdings, Inc. (Nasdaq:UCBH), down 11.5% after reporting a 92% plunge in first-quarter income.

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