LCA Vision Inc (Nasdaq:LCAV), City Bank (Nasdaq:CTBK) and Targanta Therapeutics Corp (Nasdaq:TARG) are among the new 52-week lows in Wednesday's trading among companies with market capitalizations under $1 billion.

Also included among the results: Blue Phoenix Solutions (Nasdaq:BPHX), Mothers Work Inc (Nasdaq:MWRK), Atlantic Coast Federal Corp (Nasdaq:ACFC), Accuride Corp (Nasdaq:ACW), Penford Corp (Nasdaq:PENX) and Provident Financial Holdings Inc (Nasdaq:PROV).

Here are the new 52-week lows among small caps:

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