Small-caps tumble; OPTR, CRXL, and GLDD lead gainers

Small-cap stocks tumbled on the open, pulled down by spillover selling from a decline in overseas markets fueled by a weak tone in financial and commodity shares. Today’s small-cap gainers are Optimer Pharmaceuticals (Nasdaq:OPTR), Crucell (NYSE:CRXL) and Great Lakes Dredge & Dock Corporation (Nasdaq:GLDD).

Other Market Watch highlights today included:

• Ernst & Young survey: 52% of CEOs of Russell 2000 companies expect no real economic upswing until 2010.  
• As for the crude oil, the market for black gold was down about $2 a barrel into the U.S. stock market opening and briefly printed below $60.  
• Small caps tumbled on the open, pulled down by spillover selling from a decline in overseas markets fueled by a weak tone in financial and commodity shares.  
• Emerging markets were taking a hit this morning, with stock markets in Russia slipping 9% at times overnight, while shares in Dubai off 7%.  

Small Cap Gainers:

• Optimer Pharmaceuticals soaring 75% in pre-market on Phase 3 news. See (Nasdaq:OPTR).  
• Biotech firm Crucell swings to profit in Q3; shares up over 10% in pre-market. See (Nasdaq:CRXL).  
• Morgan Joseph upgrades Great Lakes Dredge & Dock Corporation to "buy" from "hold;" shares up 8%. See (Nasdaq:GLDD).  


Small Cap Losers:

• Browne & Co. Inc. is off 36% as the marketing communication company took a hit after reporting earnings. See (NYSE:BNE).  
•  Taleo down 29% ahead of the bell after filing notification with SEC for late filing of Q3 report. See (Nasdaq:TLEO).  
• Focus Media Q3 earnings trail Street; Q4 outlook weak. Shares are slumping 35% in pre-market. See (Nasdaq:FMCN).  
• Sangamo Biosciences nerve drug fails a mid-stage trial, shares sink 60% in pre-market. See (Nasdaq:SGMO).  

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