Medicines Co. (Nasdaq:MDCO), Atlas Air Worldwide Holdings Inc. (Nasdaq:AAWW) and GT Solar International Inc. (Nasdaq:SOLR) are among the most actively traded companies in Wednesday's trading among companies with market capitalizations under $1 billion.

Also included among the results: Vanda Pharmaceuticals Inc. (Nasdaq:VNDA), Geron Corp. (Nasdaq:GERN), Century Aluminum Co. (Nasdaq:CENX), A Power Energy Generation Systems Ltd. (Nasdaq:APWR), Canadian Solar Inc. (Nasdaq:CSIQ) and JetBlue Airways Corp. (Nasdaq:JBLU).

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