Orexigen Therapeutics, Repligen and Affymetrix lead small-cap volume in pre-market

Orexigen Therapeutics Inc. (Nasdaq:OREX), Repligen Corp. (Nasdaq:RGEN) and Affymetrix Inc. (Nasdaq:AFFX) are among the most actively traded companies in Thursday's trading among companies with market capitalizations under $1 billion.

Also included among the results: Seattle Genetics (Nasdaq:SGEN), Bankrate Inc. (Nasdaq:RATE), TriQuint Semiconductor Inc. (Nasdaq:TQNT), PDL BioPharma Inc. (Nasdaq:PDLI), Volterra Semiconductor Corp. (Nasdaq:VLTR) and ClickSoftware Technologies Ltd. (Nasdaq:CKSW).

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