Acura Pharmaceuticals Inc. (Nasdaq:ACUR), Halozyme Therapeutics Inc. (Nasdaq:HALO) and Actuant Corp. (Nasdaq:ATU) are among the biggest percentage losers in Tuesday's trading among companies with market capitalizations under $1 billion.

Also included among the results: Heritage Financial Group (Nasdaq:HBOS), Pzena Investment Management Inc. (Nasdaq:PZN), Smith & Wesson Holding Corp. (Nasdaq:SWHC), Cytec Industries Inc. (Nasdaq:CYT), Hexcel Corp. (Nasdaq:HXL) and American Dental Partners Inc. (Nasdaq:ADPI).

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